Native Proteins and Derivatives

Native proteins that have not been altered by heat, chemicals, or enzymatic reaction, and associated derivatives.

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646 – 660 of 904 results

646

ABclonal Technology PE anti-h CD141/Thrombomodulin

The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin This binding results in the activation of protein C which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated Mutations in this gene are a cause of thromboembolic disease also known as inherited thrombophilia

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647

Biocare Medical, LLC Factor XIIIa Antibody - Concentrate, 1.0 ml

This is a monoclonal antibody to the A-subunit of human coagulation Factor XIII. Studies have shown it recognizes human Factor XIII Achain in both reduced and non-reduced forms. It does not react with human Factor XIII B-chain or human Factor XII. Factor XIII is a betaglobulin found in plasma and is composed of two subunits. Factor XIIIA is the catalytic subunit and is a dimer of M.W. 160,000. According to studies, Factor XIII is present in plasma as an alpha2beta2 heterodimer (M.W. 320,000); whereas in platelets, only the alpha2 unit exists. Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors (3,4). It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system (1-6). Factor XIIIa has also been used with CD34 to differentiate between dermatofibroma and dermatofibrosarcoma protuberans (3).

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648

BioVendor, LLC Human Chorionic Gonadotropin (hCG), Native Protein (10 mg)

Human Chorionic Gonadotropin (hCG) Native Protein, 10 mg. Research use only. Bioactivity approx. 5000-6000 IU/mg. Each lot is tested for biological activity which may vary with each lot. Produced from a sterile preparation of placental glucoprotein urine of pregnant women. Total MW of 36,700 Dalton. Consists of 237 amino acids, a chain-92 a.a. and b chain-145 a.a. Sterile filtered white powder, lyophilized w/ no additives. hCG is a peptide hormone used in superovulation techniques to increase the number of ovulated oocytes in lab animals. Mice are typically injected with PMSG to stimulate follicle growth and later injected with hCG to induce ovulation. hCG is made by the embryo soon after conception and later by the syncytiotrophoblast. hCG prevents the disintegration of the corpus luteum and thereby maintains progesterone production, critical for human pregnancy. hCG may affect immune tolerance of the pregnancy. Early pregnancy testing is usually based on hCG detection/measurement.

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649

Abcam Native Human IgG3 protein, 1MG

Native Human IgG3 protein is a Human Full Length protein with >95% purity and suitable for SDS-PAGE. The predicted molecular weight of ab118426 native protein is 170 kDa. - Save time and ensure accurate results - use our IgG3 protein as an isotype control - No cross-reaction from other immunoglobulin isotypes

Protein/ Peptide/ Enzyme Synonyms: Immunoglobulin heavy constant gamma 3, HDC, Heavy chain disease protein, Ig gamma-3 chain C region, IGHG3

Conjugation: Unconjugated

The product is subject to the following: Abcam Restricted Use Statement

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650

Cayman Chemical 2 3-O- 5-ChloronthrnIloy 3.3mg

Fluorescent ATP derivatives; an inhibitor of mammalian AC1, AC2, and AC5 (Kis = 80, 490, and 45 nM, respectively), B. anthracis edema factor AC toxin (Ki = 170 nM), and B. pertussis CyaA (Ki = 350 nM)